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Understanding and defining these miRNA profiles
2019-07-01
Understanding and defining these miRNA profiles helps to uncover the clinical usefulness of miRNAs. Numerous human clinical trials are currently evaluating miRNA therapeutics during various liver diseases, such as targeting miR-122 during chronic hepatitis C infection. Aside from therapeutics, the d
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br Contribution br Acknowledgments and disclosures br Introd
2019-07-01
Contribution Acknowledgments and disclosures Introduction Following HSCT a complex immune reconstitution (IR) is observed. When the infused CD34+cells (CD34+i) begin to proliferate, an increase in peripheral blood 5-Methyl-CTP is detected. Lymphocytes require more time than granulocytes in
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Next we evaluated the interatrial and
2019-06-29
Next, we evaluated the interatrial and interatrioventricular synchrony because a long contraction time between the right and left atria was observed during the SSA procedure, dissection of the atrial septum, and patch closure. We were primarily concerned with determining whether the timing of the le
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Recently denosumab demonstrated a significant delay in the o
2019-06-29
Recently, denosumab demonstrated a significant delay in the onset of detectable bone lesions in men with castration resistant prostate cancer compared to placebo . This could indicate some kind of efficacy of the compound as anticancer agent and consequently an indirect confirmation of the role of R
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br Conclusion br Conflicts of
2019-06-29
Conclusion Conflicts of interest Clinical case The worldwide estimated prevalence of cardiovascular implantable electronic device (CIED) infection is 1–2%. Prompt removal of infected devices ensures survival [1–4]. We report successful extraction of a lead from an infected CIED by using an
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Concurrent with the clinical evaluation
2019-06-29
Concurrent with the clinical evaluation of the family, the genetic findings from a molecular autopsy may help to elucidate the cause of death in the decedent, as well as provide a basis for cascade genetic testing of at-risk family members. Offering cascade genetic testing to asymptomatic relatives
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Under conditions of high cholesterol consumption an
2019-06-29
Under conditions of high cholesterol consumption, an appreciable fraction of cholesterol in bile is derived from the diet through the chylomicron pathway to the liver. Dietary cholesterol reaches the liver through the intestinal lymphatic routes as of chylomicrons, and subsequently, chylomicron remn
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In humans the two primary bile
2019-06-29
In humans, the two primary bile acids CA and CDCA make up approximately 70%–80% of the total bile KPT-330 pool. DCA is the major secondary bile acid, which may account for approximately 20% of the total bile acid pool. Among all bile acid species, the secondary bile acid LCA is highly toxic. LCA is
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March marked annual World TB Day
2019-06-29
March 24 marked annual World TB Day, this year\'s theme being “reach the 3 million” who acquire tuberculosis every year but who do not get diagnosed, treated, or cured. Why do so many patients with this life-threatening infectious disease go under the radar? One reason, as Madhukar Pai and colleague
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En segundo lugar el buen vivir siguiendo el planteamiento or
2019-06-29
En segundo lugar, el buen vivir, siguiendo el planteamiento original de la conaie de una crítica Ipratropium Bromide la economía del mercado, plantea como uno de sus ejes principales la creación de un sistema económico social y solidario que reconoce al ser humano como sujeto y fin que “tiene por ob
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En conclusi n vivir bien
2019-06-29
En conclusión, vivir bien/buen vivir no son por el momento nuevos paradigmas, pese a que, por ejemplo, los autores del Plan Nacional para el Buen Vivir de Ecuador (2009-2013) se referan a una transición del concepto de desarrollo al buen vivir en los términos de un “cambio de para-digma”. En estos t
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Sin embargo m s all de las coincidencias
2019-06-29
Sin embargo, más allá de las coincidencias sobre qué hacer con y en el exilio, las significativas posiciones que se presentaron en sus páginas estuvieron lejos de mantener una posición unívoca. Como sugirió Gago, en Controversia pueden reconocerse al menos tres figuras: (1) el exilio como privilegio
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A comienzos del siglo xx en el
2019-06-29
A comienzos del siglo xx, en el imaginario criollista y en un sentido similar al que intentamos planear aquí en lo que RI-1 las disidencias sexuales respecta, el personaje inmigrante permanecía siempre en un segundo plano respecto del héroe, siempre criollo. Al inmigrante italiano, así como les suce
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Adriana Kanzepolsky emple la met
2019-06-29
Adriana Kanzepolsky empleó la metáfora del dibujo para insinuar la dimensión creativa de la selección editorial de los origenistas en su estudio Un dibujo del mundo. Extranjeros en Orígenes. Kanzepolsky describió cómo se modeló un esquema del mundo según los criterios de los colaboradores de una emp
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In this study we analyzed
2019-06-29
In this study, we analyzed the biological effects of two novel GATA2 mutations, which were identified in adult de novo AML patients. Materials and methods The diagnosis of AML was based on the morphology, histopathology, the expression of leukocyte differentiation cyclin dependent kinase inhibit
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