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gssg Heat shock facilitates the folding of various proteins
2019-06-13
Heat shock facilitates the folding of various proteins as mediated by the HSP family and can stabilize mutant proteins. HS has been reported to facilitate maturation of WT-HERG as well as mutant HERG by activating the HSF family [15]. HSF-1, 2, and 4 were reported to be expressed in humans. HSF-1 is
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br VIII Si atendemos a que Pablo del Prado en
2019-06-13
VIII. Si atendemos fdps que Pablo del Prado en su Directorio espiritual, todavía en el año de 1650, incorporaba numerosas oraciones para la comunión espiritual indígena, junto a recomendaciones sobre la exclusión de la efectiva, no parece probable que se alcanzara nunca una normalización del hech
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Recordemos que en diciembre de se celebr en Lima
2019-06-13
Recordemos que en diciembre de 1938 se celebró en Lima la Octava Conferencia Internacional de los Estados Americanos, donde se analizó la Segunda Guerra Mundial y las posibles consecuencias para América, así como el rol de Estados Unidos, aunque no se aprobó ninguna acción colectiva. La Declaración
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NCS is a rare syndrome In case series of NCS
2019-06-13
NCS is a rare syndrome. In case series of NCS 14–47% were associated with of lymphoproliferative disorders [reviewed in [12]]. Survival is usually dictated by the underlying disease and short in the setting of aggressive malignancies. Since NCS may be a manifestation of an underlying malignancy it h
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br Pathophysiology and risk factors Patient with CIED may ge
2019-06-12
Pathophysiology and risk factors Patient with CIED may get infected at time of initial ptc124 or during pocket revision for device change or upgrade [8,2]. Device erosions are by default infected but most commonly are a secondary manifestation of slow growing underlying infection [8]. Pocket infe
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br Conflict of interest br Introduction For decades
2019-06-12
Conflict of interest Introduction For decades, cancer has been the leading cause of death in Taiwan. In 2012, esophageal cancer was the eighth most common cancer globally, with 456,000 new cases presenting that year. Esophageal cancer caused approximately 400,000 deaths in 2012, up from 345,00
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Numerous clinical trials phase II and phase III
2019-06-12
Numerous clinical trials (phase II and phase III) have been then designed to evaluate the efficacy of denosumab in oncology mainly in breast and prostate bone metastases (Table 1). These studies revealed that denosumab reduced significantly bone turnover markers similarly to osteoporotic patients. M
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zip inhibitor All patients engrafted patient Patient develop
2019-06-12
All patients engrafted; 1 patient (Patient 6) developed secondary graft rejection following an A antigen mismatched graft from a male sibling and went on to receive a VUD HSCT with a female donor. There were no major conditioning related toxicities. Bacterial infections occurred in 6 patients prior
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br In a reanalysis of our results Michelle
2019-06-12
In a reanalysis of our results, Michelle Remme and colleagues (October, 2015) found that “secondary schooling might [even] be as good an HIV investment as male circumcision”, not to mention more expensive biomedical options. As Remme and colleagues rightly point out, we had excluded from our cost-
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Subsequently more detailed mapping was performed to identify
2019-06-12
Subsequently, more detailed mapping was performed to identify the Purkinje potential preceding the QRS onset of the PVCs in their region of origin (Fig. 2B). Radiofrequency ablation was performed at the site of the earliest Purkinje potential preceding the local ventricular potential (Fig. 2C and D)
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However she had an attack on Day The
2019-06-12
However, she had an attack on Day 7. The ECG monitor was normal until 4:25 AM (Fig. 1a). ST segment elevation was evident, and the patient experienced chest pain at 4:30 AM (Fig. 1b). ST segment elevations were seen in leads II, III, and aVF on the 12-lead ECG. As sublingual nitroglycerin was ineffe
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Surgery especially modified radical mastectomy is the gold
2019-06-12
Surgery, especially modified radical mastectomy, is the “gold standard” for the treatment of male breast cancer. Postoperative adjuvant radiotherapy is recommended for male patients with large breast cancer and axillary lymph node and chest muscle involvement; it can reduce the risk of local cancer
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Introduction Bone metastases are a common manifestation of
2019-06-12
Introduction Bone metastases are a common manifestation of cancer [1]. Most patients present with pain and impaired mobility, while others can develop complications such as pathological fractures and buy 1-Deoxynojirimycin of the spinal cord or cauda equina [2]. Many randomized studies have been co
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br Discussion PLSVC can be encountered for
2019-06-12
Discussion PLSVC can be encountered for the first time during electrophysiological procedures. It is the most common variation in the thoracic venous system and is estimated to be present in 0.3–0.5% of the general population and in 5–10% of patients with other congenital heart defects [3]. It c
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Our findings show that primary prevention
2019-06-12
Our findings show that primary prevention ICD recipients experienced an impaired QOL on vitality subscales, which were included in the physical health domain, compared to secondary prevention ICD recipients. Similarly, Berg et al. also found that ICD patients with a primary prevention indication had
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