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Chronic myelogenous leukemia blast crisis is highly refracto
2019-05-29
Chronic myelogenous leukemia blast crisis is highly refractory to standard induction chemotherapy, with a response rate of less than 20–30% [12,13]. In patient\'s with Imatinib resistant disease Dastanib and Nilotinib can help achieve hematological response however neither drug has been reported to
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br Discussion The natural history of
2019-05-29
Discussion The natural history of PMF is characterized by the possibility of blastic transformation in approximately 20% of all the cases [9]. Several factors might predict leukemic transformation, including percentage of circulating blasts, low platelets count and the presence of an unfavorable
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Clinical symptoms consist of the pacemaker syndrome includin
2019-05-29
Clinical symptoms consist of the pacemaker syndrome, including palpitations and hemodynamic instability, as in our case. The definitive management of RNRVAS requires sufficient time for the atrial tissue to recover from the refractory period. Barold et al. reviewed several general modes that could p
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La sensaci n de desmoronamiento y de v rtigo
2019-05-29
La sensación de desmoronamiento y de vértigo nace en “Lumbre en el aire” de la confusión de lo terrestre con lo estelar o sideral. Mientras los signos “jardines”, “mar” o “rocas” remiten a realidades telúricas, “cielo”, “astros”, “cometas”, “aerolitos” “galaxia” sitúan al lector en la dimensión cósm
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Under conditions of high cholesterol consumption an
2019-05-28
Under conditions of high cholesterol consumption, an appreciable fraction of cholesterol in bile is derived from the diet through the chylomicron pathway to the liver. Dietary cholesterol reaches the liver through the intestinal lymphatic routes as of chylomicrons, and subsequently, chylomicron remn
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One study in Pakistan showed that lay health
2019-05-28
One study in Pakistan showed that cyclic gmp lay health workers could deliver health promotion materials for blood pressure and achieve effective lowering of blood pressure levels in the population. And the ability of non-physician health workers to detect and manage diabetes and high blood pressur
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Air pollution also has a
2019-05-28
Air pollution also has a substantial effect on the wellbeing of people worldwide. This pollution can consist of sulfur dioxide, ozone, nitrogen dioxide, and fine-particulate Lomustine of less than 2·5 μm in diameter (PM). 92% of the global population is exposed to higher-than-recommended concentrat
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Reframing non communicable diseases NCDs to spur
2019-05-28
Reframing non-communicable diseases (NCDs) to “spur a sense of urgency” and “focus attention on effective system-wide interventions” makes sense. With almost three-quarters of NCD deaths now occurring in low-income and middle-income countries (LMICs), the increasing burden of NCDs already has severe
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br The indications for ICD placement for the secondary preve
2019-05-28
The indications for ICD placement for the secondary prevention of sudden cardiac death Some patients with underlying ddr1 disease and/or LV dysfunction die from tachyarrhythmias even after ICD placement [18]. However, no arrhythmic deaths occurred during the implantation or during the follow-up p
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br Discussion There were recurrences out of patients of
2019-05-28
Discussion There were 2 recurrences (8.3%¸ 2 out of 24 patients), 1 of which occurred immediately following the procedure. In this patient, SVT was not induced with programmed atrial or ventricular stimulations after the ablation of accessory pathway. Ventriculoatrial conduction was through the A
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glycosylase This Ca overload activates the forward mode of
2019-05-28
This Ca2+ overload activates the forward mode of the Na+/Ca+ exchanger (NCX), increases the transient inward current (Iti), and induces ventricular arrhythmias due to delayed after depolarizations (DADs). Subtypes of CPVT Several subtypes of CPVT have been reported (Table 1). The most common typ
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En Sumar restar Carlos Fuentes efectivamente colabora con
2019-05-28
En Sumar, restar, Carlos Fuentes efectivamente colabora con Kátharsis; elige, con cierta ironía, el diálogo escénico, la forma clásica señalada por Aristóteles para la catarsis; pone en acción paricalcitol tres personajes, un griego (Pitágoras), a una forma pura (el número uno) y a un mexicano (un v
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Thomas Hoeksema por su parte explica la paradoja del
2019-05-28
Thomas Hoeksema, por su parte, explica la paradoja del título del siguiente modo: “la destrucción (fuego) está moderada por la estabilidad y la armonía (reposo). La relación entre estas dos fuerzas es multidimensional y dialéctica”. Para Hoeksema, el segundo volumen poético de Pacheco se debe entend
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Con respecto de la importancia del periodo colonial hay
2019-05-27
Con respecto de la importancia del periodo colonial, hay dos ideas en sus reflexiones que quisiera rescatar: la primera es su consideración de esta época como el de la sociedad mexicana, pues es en esta etapa cuando se produce la “creación de una nueva sociedad”, cuyo desarrollo “presenta un materi
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Feeding stimulates gallbladder contraction emptying its cont
2019-05-27
Feeding stimulates gallbladder contraction, emptying its contents into the upper part of the small intestine, where CBAs activate pancreatic lipase to release monoglycerides and free fatty acids from triglycerides. Mixed micelles with monoglycerides, fatty acids, cholesterol, and fat-soluble vitamin
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