• Rabies has no cure and by the

  2019-06-18

  

  Rabies has no cure, and by the time of clinical onset it is invariably fatal. More than 95% of deaths occur in Africa and Asia, 80% of which are in people living in rural, underserved populations, most of whom are children. Community awareness about the power of preventing dog bites and of life-savi

• Almost all the information we have on clinical

  2019-06-18

  

  Almost all the information we have on clinical epidemiology of patients with ABT 724 trihydrochloride failure is collected in North America or in western European countriesTherefore, the work of Hisham Dokainish and colleagues in this issue of , is very welcome. Their study provides a clear picture

• Nakai et al showed that RTc and

  2019-06-18

  

  Nakai et al. showed that RTc and Tpeak-end dispersion can be used to evaluate the spatial distribution of myocardial repolarization [15,16]. We measured RTc and Tpeak-end dispersion in the acute and chronic periods in the case reported herein. Both variables were increased during the acute period af

• br Commentary The concept of

  2019-06-18

  

  Commentary The concept of entrainment mapping for ablation of VT is that targeting the site will interrupt the reentrant VT circuit. This site must be located, not only within the circuit, but also in a protected and relatively narrow isthmus. During entrainment mapping, the QRS morphology, S-QRS

• The electrophysiological mechanisms underlying high frequenc

  2019-06-18

  

  The electrophysiological mechanisms underlying high frequency activity observed in the PLA during SRAF could be reentry (rotor) or focal discharges (triggered activity). To discriminate between these mechanisms, we perfused ryanodine (10–40μM) or caffeine (5mM) to abolish calcium overload-mediated t

• br Conclusion br Conflict of interest br

  2019-06-18

  

  Conclusion Conflict of interest Introduction Dermatofibrosarcoma protuberans (DFSP) is a rare soft-tissue neoplasm that was first identified by Taylor, RW in 1890. It was then described in 1924 by Darier, J and Ferrand, M as a progressive recurrent dermatofibroma, and was later termed DFSP

• br How do you manage patients on

  2019-06-18

  

  How do you manage patients on intravenous bone-targeted agents who require dental work? For patients who are on IV bisphosphonate therapy and require dento-alveolar procedures there is a suggestion that prophylactic antibiotic use around the procedure may be helpful in reducing ONJ risk [45,49].

• The multivariable Cox regression model

  2019-06-18

  

  The multivariable Cox regression model also showed that patients who were divorced, separated, or widowed had a significantly worse outcome than patients who were married or single; the mortality rate for Divorced, Separated or Widowed PLB patients was estimated to be 1.4 times that for married pati

• br Discussion Furthermore most of the

  2019-06-18

  

  Discussion Furthermore most of the previously described cases with a solitary lesion affecting bone involved the craniofacial bones [2–7], and only a few cases affected the appendicular skeleton. Several affected extra-craniofacial sites have been sporadically reported, for example: femur [8], ti

• Introduction Neuroblastoma NB which arises from

  2019-06-18

  

  Introduction Neuroblastoma (NB), which arises from embryonal neural crest cells, is the most common extra-cranial solid tumor of childhood and accounts for more than 15% of all child cancer death [1,2]. Patients with NB frequently manifest disseminated disease at first visit and prognosis of these

• br Disclosures and funding sources br Conflicts of

  2019-06-18

  

  Disclosures and funding sources Conflicts of interest Introduction In 1994, Leenhardt et al. first described electrocardiogram (ECG) findings of torsades de pointes and QT prolongation in patients without demonstrable structural AH 7614 disease, with the torsades de pointes initiated by sho

• 3\'-O-(2-nitrobenzyl)-2\'-dATP El an lisis de Close

  2019-06-18

  

  El análisis de Close merece una continuación. En efecto, la narrativa mexicana actual cuenta con otros autores de novelas de crímenes que se mantienen alejados de los tópicos necro-pornográficos misóginos y del gusto sensacionalista y moralista. En lo que sigue abogaremos por la inclusión de Alejan

• La fotograf a reforz el car cter militarista

  2019-06-18

  

  La fotografía reforzó el carácter militarista del pgt-pc. El ajusticiamiento de Zepeda Martínez perdió su fuerza política al carecer de MMAF los mecanismos de propaganda que acompañan una acción de este tipo. Si bien los recursos gráficos explotados por el periodismo difundieron la muerte del cónsul

• Funding None Declaration of interests br Abstract Background

  2019-06-18

  

  Funding None. Declaration of interests Abstract Background Millennium Development Goal (MDG) 6 focused on halting the spread of HIV/AIDS. Since this goal was established, more development assistance for health has been devoted to combat HIV/AIDS in low-income and middle-income countries than an

• In summary we have established

  2019-06-17

  

  In summary, we have established an animal model of human NB bone metastasis in which COX-2/PGE2 plays a critical role. We provide pre-clinical data supporting the use of COX-2 inhibitors in the treatment of bone metastases in NB. Conflict of interest statement Introduction Desmoplastic fibrom

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