• PRRSV is a single stranded positive sense enveloped RNA

  2020-01-14

  

  PRRSV is a single-stranded, positive-sense enveloped RNA virus in the family Arteriviridae of the order Nidovirales (Meng et al., 1994, 1996). The PRRSV rxr receptor is approximately 15 kb in length and contains eleven known open reading frames (ORFs) (Snijder et al., 2013). The 3′ end of the genom

• br Acknowledgments We thank our colleagues who

  2020-01-14

  

  Acknowledgments We thank our colleagues who have contributed to our understanding of the Illumina for 5 ng DNA synthesis and the structure and function of APC/C, and apologize to those whose work we were unable to cite here. We thank J. Rajan Prabu for making the movies showing APC/C conformatio

• calpain inhibitor Several functions of FAT have been suggest

  2020-01-14

  

  Several functions of FAT10 have been suggested. It has been shown that FAT10 binds noncovalently to the mitotic spindle checkpoint protein MAD2 and that this binding might cause chromosome instability in the cancer calpain inhibitor overexpressing FAT10 (Liu et al., 1999, Ren et al., 2006). In othe

• The mammalian two hybrid results described

  2020-01-14

  

  The mammalian two-hybrid results described above were all obtained in 293T cells, and thus the higher RLU observed specific to the hCrm1 fusion could be consistent with human Cordycepin mg having an unknown activator that interacts with hCrm1 HEAT repeat 9A and somehow facilitates Crm1-Rev/RRE funct

• Previously published results on this topic

  2020-01-14

  

  Previously published results on this topic are inconsistent. Stressin1-A, a novel CRF1 receptor agonist, increased anxiety-like behavior in the social interaction and shock-probe tests [51]. Pharmacological blockade of CRF1 (NBI-30775) reversed both CRF-induced increases in startle and CRF-induced d

• Several mechanisms are implicated in lipid induced insulin r

  2020-01-14

  

  Several mechanisms are implicated in lipid-induced insulin resistance in muscle, including oxidative stress (Koves et al., 2008, Zhang et al., 2011, Muoio and Neufer, 2012). Mitochondrion is a major source of ROS production. The oxidation of pyruvate and fatty Hydroxyurea yielding acetyl-CoA occurs

• Phytophthora capsici is a phytopathogenic oomycete a

  2020-01-14

  

  Phytophthora capsici is a phytopathogenic oomycete, a lineage of eukaryotic microorganisms in the kingdom Stramenopila, which causes devastating diseases on many economically important vegetables [15]. Hyps are present in the Phytophthora cell wall proteins [16] and phytotoxic elicitor proteins [17]

• Microcystin-LR Importantly our in vivo data

  2020-01-14

  

  Importantly, our in vivo data fit to the in vitro data, further confirming the synergistic effect of XJD and gefitinib on the inhibition of lung cancer and the regulation of SP1, HOTAIR, and EP4 Microcystin-LR levels. The doses of XJD used were based on our previous in vivo study (Zhao et al., 2016

• Ac-IETD-pNA Results from experiments in model systems have s

  2020-01-14

  

  Results from experiments in model systems have suggested that the DPRs translated from the HRE of C9ORF72 are toxic and play a role in disease pathogenesis (reviewed in Taylor et al. (2016)). Although the DPRs are present in neurons and glia in various regions of the central nervous system (CNS) ear

• Introduction Ubiquitylation is a post translational modifica

  2020-01-14

  

  Introduction Ubiquitylation is a post-translational modification which impacts almost every biological process in the cell. Dysregulation of the ubiquitylation pathway is associated with several diseases, including cancer, neurodegenerative disorders, and immunological dysfunctions. Single ubiquiti

• br E intracellular localization br Regulation

  2020-01-14

  

  E1 intracellular localization Regulation of E1 by other post-translational modifications Concluding remarks Acknowledgments We apologize to those whose work was not included because of space considerations or whose papers were unintentionally omitted. We thank Dr Peter Bullock (Tufts Uni

• E protein expressed in a

  2020-01-14

  

  E1 protein expressed in a plasmid encoding codon-optimized canine oral papillomavirus (COPV) led to therapeutic immunization of COPV-infected Beagle dogs [25], [26], which was better than that achieved with plasmids encoding E2 or E7 COPV. Moreover, E1 and E2 from cottontail rabbit papillomavirus (C

• Although DGK is a lipid modulating enzyme the role of

  2020-01-13

  

  Although DGKγ is a lipid-modulating enzyme, the role of DGKγ in integral cell metabolism has not been reported. We found that DGKγ made a difference on cell metabolism profile in HCC cells, which may be caused partially by the downregulation of GLUT1. Glucose is a major source of energy, and decreas

• The sequence identity of CYP A

  2020-01-13

  

  The sequence identity of CYP3A163 with CYP3A sequences from other species is maximum in reptiles ranging (75-91)%, gradually decreasing from Isoniazid (63-71)% to mammals 62% to downwards based on evolutionary distances. The high level of homology with CYP3A77 in Alligator mississippiensis suggest t

• Khan et al investigatedAnomalin a pyranocoumarin constituent

  2020-01-13

  

  Khan et al. investigatedAnomalin 44, a pyranocoumarin constituent of S. divaricata, which exhibits potent anti-inflammatory activity. The anomalin 44 dose-dependently inhibited inducible nitric oxide synthase (iNOS) and cyclooxygenase-2 (COX-2) mRNA and protein expression in LPS-stimulated RAW 264.7

16103 records 931/1074 page Previous Next First page 上5页 931932933934935 下5页 Last page